Archive - The Dependent Variable

Acid–base, Part 2: A question of independence

Or a question of neutrality?

Sep 30 • The Dependent Variable

Acid–base, Part 1: A question of balance

Whose hydrogen is it anyway?

Sep 24 • The Dependent Variable

The Afterload Problem

Blood pressure is not afterload. SVR is not afterload. And the same arterial load does not impose the same burden on every heart.

Sep 14 • The Dependent Variable

The Pressure That Wasn’t Measured

What a new study of mean systemic filling pressure tells us about calculated variables, causal inference and venous return.

Sep 9 • The Dependent Variable

The Preload Problem

Driver or operating point?

Sep 7 • The Dependent Variable

August 2026

What Actually Happens When We Give Fluid or Vasopressors?

The physiology of where the blood goes

Aug 31 • The Dependent Variable

Episode VIII: The Dependent Variable

Venous Return Wars

Aug 24 • The Dependent Variable

Episode VII: The Last Equation

Venous Return Wars

Aug 17 • The Dependent Variable

Episode VI: The Bathtub Menace

Venous Return Wars

Aug 10 • The Dependent Variable

Episode V: The Reservoir Awakens

Venous Return Wars

Aug 3 • The Dependent Variable

July 2026

Episode IV: The Phantom Pressure

Venous Return Wars

Jul 25 • The Dependent Variable

Episode III: Return of the Elastic State

Venous Return Wars

Jul 21 • The Dependent Variable

#nojs-banner { position: fixed; bottom: 0; left: 0; padding: 16px 16px 16px 32px; width: 100%; box-sizing: border-box; background: red; color: white; font-family: -apple-system, "Segoe UI", Roboto, Helvetica, Arial, sans-serif, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol"; font-size: 13px; line-height: 13px; } #nojs-banner a { color: inherit; text-decoration: underline; } This site requires JavaScript to run correctly. Please turn on JavaScript or unblock scripts